Sequencing Endocrine Therapy for Metastatic Breast Cancer: What Do We Do After Disease Progression on a CDK4/6 Inhibitor?

被引:0
作者
Jing Xi
Cynthia X. Ma
机构
[1] Washington University School of Medicine,Section of Medical Oncology, Division of Oncology, Department of Internal Medicine
[2] Washington University School of Medicine,Siteman Cancer Center
来源
Current Oncology Reports | 2020年 / 22卷
关键词
Metastatic breast cancer (MBC); Hormone receptor-positive (HR+) and HER2-negative (HER2−) breast cancer; Estrogen receptor-positive (ER+) breast cancer; CDK4/6 inhibitor; Endocrine therapy; Biomarkers; Sequencing of therapy; Resistance mechanisms; Clinical trials; PI3K inhibitor; mTOR inhibitor; FGFR inhibitor; CDK inhibitor; Aurora kinase inhibitor; RB1; PIK3CA; ESR1; Palbociclib; Abemaciclib; Ribociclib; Alpelisib; Everolimus; Selective estrogen receptor downregulator (SERD); Fulvestrant; Aromatase inhibitor; Targeted therapy;
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