An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression

被引：0
作者：
Yufeng Qin
John D. Roberts
Sara A. Grimm
Fred B. Lih
Leesa J. Deterding
Ruifang Li
Kaliopi Chrysovergis
Paul A. Wade
机构：
[1] Eukaryotic Transcriptional Regulation Group,
[2] Epigenetics and Stem Cell Biology Laboratory,undefined
[3] National Institute of Environmental Health Sciences,undefined
[4] Integrative Bioinformatics Group,undefined
[5] Epigenetics and Stem Cell Biology Laboratory,undefined
[6] National Institute of Environmental Health Sciences,undefined
[7] Mass Spectrometry Research & Support Group,undefined
[8] Epigenetics and Stem Cell Biology Laboratory,undefined
[9] National Institute of Environmental Health Sciences,undefined
来源：
Genome Biology | / 19卷
关键词：
Microbiome; Obesity; Cancer; Colorectal cancer; Epigenetics; Transcription factor; Gene expression; Histone methylation; Histone acetylation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 31 条
  • [1] An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression
    Qin, Yufeng
    Roberts, John D.
    Grimm, Sara A.
    Lih, Fred B.
    Deterding, Leesa J.
    Li, Ruifang
    Chrysovergis, Kaliopi
    Wade, Paul A.
    GENOME BIOLOGY, 2018, 19
  • [2] Diet, inflammation and the gut microbiome: Mechanisms for obesity-associated cognitive impairment
    Leigh, Sarah-Jane
    Morris, Margaret J.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2020, 1866 (06):
  • [3] Protective Effects of Anthocyanins in Obesity-Associated Inflammation and Changes in Gut Microbiome
    Jayarathne, Shasika
    Stull, April J.
    Park, Oak-Hee
    Kim, Jung Han
    Thompson, Leslie
    Moustaid-Moussa, Naima
    MOLECULAR NUTRITION & FOOD RESEARCH, 2019, 63 (20)
  • [4] Understanding the Role of the Gut Microbiome and Microbial Metabolites in Obesity and Obesity-Associated Metabolic Disorders: Current Evidence and Perspectives
    Natalia Vallianou
    Theodora Stratigou
    Gerasimos Socrates Christodoulatos
    Maria Dalamaga
    Current Obesity Reports, 2019, 8 : 317 - 332
  • [5] Understanding the Role of the Gut Microbiome and Microbial Metabolites in Obesity and Obesity-Associated Metabolic Disorders: Current Evidence and Perspectives
    Vallianou, Natalia
    Stratigou, Theodora
    Christodoulatos, Gerasimos Socrates
    Dalamaga, Maria
    CURRENT OBESITY REPORTS, 2019, 8 (03) : 317 - 332
  • [6] Apigenin Alleviates Obesity-Associated Metabolic Syndrome by Regulating the Composition of the Gut Microbiome
    Qiao, Yuan
    Zhang, Zhichun
    Zhai, Yuanyuan
    Yan, Xu
    Zhou, Wenling
    Liu, Hao
    Guan, Lingling
    Peng, Liang
    FRONTIERS IN MICROBIOLOGY, 2022, 12
  • [7] Does Gut-Microbiome Interaction Protect against Obesity and Obesity-Associated Metabolic Disorders?
    Zawada, Agnieszka
    Rychter, Anna Maria
    Ratajczak, Alicja Ewa
    Lisiecka-Masian, Agata
    Dobrowolska, Agnieszka
    Krela-Kazmierczak, Iwona
    MICROORGANISMS, 2021, 9 (01) : 1 - 19
  • [8] The complex link between the gut microbiome and obesity-associated metabolic disorders: Mechanisms and therapeutic opportunities
    Zhang, Kexin
    Zhang, Qi
    Qiu, Hongyan
    Ma, Yanhui
    Hou, Ningning
    Zhang, Jingwen
    Kan, Chengxia
    Han, Fang
    Sun, Xiaodong
    Shi, Junfeng
    HELIYON, 2024, 10 (17)
  • [9] Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility
    Sonia Baig
    Ehsan Parvaresh Rizi
    Muhammad Shabeer
    Vanna Chhay
    Shao Feng Mok
    Tze Ping Loh
    Faidon Magkos
    Antonio Vidal-Puig
    E. Shyong Tai
    Chin Meng Khoo
    Sue-Anne Toh
    Nutrition & Metabolism, 13
  • [10] Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility
    Baig, Sonia
    Rizi, Ehsan Parvaresh
    Shabeer, Muhammad
    Chhay, Vanna
    Mok, Shao Feng
    Loh, Tze Ping
    Magkos, Faidon
    Vidal-Puig, Antonio
    Tai, E. Shyong
    Khoo, Chin Meng
    Toh, Sue-Anne
    NUTRITION & METABOLISM, 2016, 13 : 1 - 8
1234