Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

被引:0
|
作者
Helfrid Hochegger
Shunichi Takeda
Tim Hunt
机构
[1] Helfrid Hochegger is at the Genome Damage and Stability Centre,Shunichi Takeda is at the Department of Radiation Genetics
[2] University of Sussex,undefined
[3] Falmer Brighton,undefined
[4] BN1 9RQ,undefined
[5] UK.,undefined
[6] Graduate School of Medicine,undefined
[7] Kyoto University,undefined
[8] Sakyo-ku,undefined
[9] Kyoto 606-8501,undefined
[10] Japan.,undefined
[11] Tim Hunt is at Clare Hall Laboratories Cancer Research UK,undefined
[12] Blanche Lane,undefined
[13] South Mimms,undefined
[14] EN6 3LD,undefined
[15] UK.,undefined
来源
Nature Reviews Molecular Cell Biology | 2008年 / 9卷
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摘要
Cell-cycle transitions in higher eukaryotes are regulated by different cyclin-dependent kinases (CDKs) and cyclins. Recent work using gene-targeted mice has led to a revision of this model and revealed overlapping and essential roles of different CDKs and cyclins.
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页码:910 / 916
页数:6
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