Influence of early high-dose steroid treatment on Bell's palsy evolution

被引：0

作者：

G. Lagalla

F. Logullo

P. Di Bella

L. Provinciali

M. G. Ceravolo

机构：

[1] Neurorehabilitation Clinic,

[2] Department of Neurosciences,undefined

[3] Umberto I Hospital,undefined

[4] University of Ancona,undefined

[5] Via Conca 1,undefined

[6] I-60020 Torrette (AN),undefined

[7] Italy,undefined

[8] Neurological Clinic Department of Neurosciences,undefined

[9] University of Ancona,undefined

[10] Ancona,undefined

[11] Italy,undefined

来源：

Neurological Sciences | 2002年 / 23卷

关键词：

Key words High-dose corticosteroids; Early treatment; Bell's palsy;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The objective of this double-blind, randomized, placebo-controlled study was to test the efficacy of high-dose prednisone, administered as early as possible, in modifying the natural progression of Bell's palsy. Sixty-two consecutive patients, enrolled within 72 hours of facial palsy onset, were assigned to high dose intravenous prednisone in combination with intramuscular polyvitaminic therapy (group A) or polyvitaminic therapy alone (group B). Clinical grading of facial muscle strength and length of absence from work were evaluated. An early worsening of facial muscle strength was observed in controls, leading to the divergence in the trends of the grading scores in the two groups; this result was not confirmed in the long-term follow-up. Treated patients returned to work earlier than controls. In conclusion, early treatment based on high-dose corticosteroids slightly accelerates spontaneous improvement in Bell's palsy.

引用

页码：107 / 112

页数：5