What is causing the corneal ulcer? Management strategies for unresponsive corneal ulceration

被引:0
作者
G Amescua
D Miller
E C Alfonso
机构
[1] Bascom Palmer Eye Institute,
[2] University of Miami Miller School of Medicine,undefined
来源
Eye | 2012年 / 26卷
关键词
corneal ulcer; infectious keratatis treatment; approach to corneal ulcers;
D O I
暂无
中图分类号
学科分类号
摘要
Infectious keratitis represents a significant cause of ocular morbidity in the United States. The work-up and treatment of presumed infectious keratitis (PIK) has changed in the past two decades. The development of newer topical antibiotics has enabled broad-spectrum antibiotic coverage with good tissue penetration. The majority of PIK cases respond well to this strategy. The small numbers of cases that do not respond to the treatment are the cases that offer a diagnostic and therapeutic challenge. This review will describe different algorithms that can be followed for the successful management of patients with difficult or progressive PIK. These algorithms are based on scientific work and on our empirical clinical experience. The review will also present three different clinical cases of PIK that were managed according to the algorithms presented in this review.
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页码:228 / 236
页数:8
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[1]  
Pepose JS(1992)Divergent approaches to the management of corneal ulcers Am J Ophthalmol 114 630-632
[2]  
Wilhelmus KR(2010)Epidemiology of ulcerative keratitis in Northern California Arch Ophthalmol 128 1022-1028
[3]  
Jeng BH(2005)Epidemiological and microbiological diagnosis of suppurative keratitis in Gangetic West Bengal, eastern India Indian J Ophthalmol 53 17-22
[4]  
Gritz DC(2002)Indecision about corticosteroids for bacterial keratitis: an evidence-based update Ophthalmology 109 835-842
[5]  
Kumar AB(1999)Incidence of contact lens-associated microbial keratitis and its related morbidity Lancet 354 181-185
[6]  
Basak SK(2006)Evidence based review of moxifloxacin Int Ophthalmol Clin 46 61-72
[7]  
Basak S(2010) susceptibility of bacterial keratitis isolates to fourth-generation fluoroquinolones Eur J Ophthalmol 20 300-305
[8]  
Mohanta A(1992)Community care of corneal ulcers Am J Ophthalmol 114 531-538
[9]  
Bhowmick A(2010)Therapeutic keratoplasty for microbial keratatis Curr Opin Ophthalmol 21 293-300
[10]  
Wilhelmus KR(2000)Corneal biopsy in the management of pregressive microbial keratitis Am J Ophthalmol 129 571-576