Clinical impact of thrombus aspiration during primary percutaneous coronary intervention in acute myocardial infarction with occluded culprit

被引：11

作者：

Shiraishi J. ^{[1
]}

Kohno Y. ^{[1
]}

Nakamura T. ^{[3
]}

Yanagiuchi T. ^{[1
]}

Hashimoto S. ^{[1
]}

Ito D. ^{[1
]}

Kimura M. ^{[1
]}

Matsui A. ^{[1
]}

Yokoi H. ^{[1
]}

Arihara M. ^{[2
]}

Hyogo M. ^{[1
]}

Shima T. ^{[1
]}

Sawada T. ^{[1
]}

Matoba S. ^{[3
]}

Yamada H. ^{[3
]}

Matsumuro A. ^{[3
]}

Shirayama T. ^{[3
]}

Kitamura M. ^{[4
]}

Furukawa K. ^{[5
]}

机构：

[1] Department of Cardiology, Kyoto First Red Cross Hospital, Honmachi, Higashiyama-ku, Kyoto

[2] Department of Emergency Medicine, Kyoto First Red Cross Hospital, Honmachi, Higashiyama-ku, Kyoto

[3] Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto

[4] Department of Cardiology, Kyoto Second Red Cross Hospital, Kyoto

[5] Department of Cardiology, Tanabe Central Hospital, Kyotanabe

来源：

Cardiovascular Intervention and Therapeutics | 2015年 / 30卷 / 1期

关键词：

Acute myocardial infarction; Aspiration; Thrombectomy;

D O I：

10.1007/s12928-014-0282-4

中图分类号：

学科分类号：

摘要：

Data regarding clinical efficacy of thrombectomy in patients with acute myocardial infarction (AMI) have been still limited in Japan. Using the AMI-Kyoto Multi-Center Risk Study database, the clinical background characteristics, angiographic findings, primary percutaneous coronary intervention (PCI) results and in-hospital prognoses were retrospectively compared between AMI patients with totally occluded infarct-related artery (IRA) (TIMI flow grade 0) undergoing thrombus aspiration during primary PCI (with-aspiration patients, n = 568) and those without thrombus aspiration (without-aspiration patients, n = 266). The with-aspiration patients were more likely to have higher TIMI grade in the IRA immediately after primary PCI, and had a lower in-hospital mortality rate than the without-aspiration patients. According to a multivariate analysis, thrombectomy as well as stent usage was found to be independent predictor of final TIMI flow grade ≥2 in the IRA, and the final TIMI flow grade ≥2 in the IRA was found to be an independent factor for in-hospital survival. These results suggest that among real-world, unselected Japanese AMI patients with totally occluded IRA on initial coronary angiography, thrombus aspiration is an effective adjunctive therapy during primary PCI to improve final epicardial coronary flow in the IRA, which might lead to better in-hospital prognosis. © 2014, Japanese Association of Cardiovascular Intervention and Therapeutics.

引用

页码：22 / 28

页数：6

共 27 条

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