Scratching the itch with cryo-EM

被引：0
作者：
Jagannath Maharana
Parishmita Sarma
Arun K. Shukla
机构：
[1] Indian Institute of Technology,Department of Biological Sciences and Bioengineering
来源：
Nature Chemical Biology | 2022年 / 18卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Cryo-EM structures of Mas-related G-protein-coupled receptors (MRGPRs) that are involved in the allergic reaction and itch response reveal structural insights into their activation mechanism, and offer the potential to discover new therapeutic agents for pain and hypersensitivity reactions.
引用
收藏
页码：242 / 243
页数：1
相关论文
共 14 条
[1]  
Ikoma A(2006)undefined Nat. Rev. Neurosci. 7 535-547
[2]  
Bader M(2014)undefined Pharmacol. Rev. 66 1080-105
[3]  
Liu Q(2009)undefined Cell 139 1353-1365
[4]  
Yu H(2019)undefined eLife 8 e48431-175
[5]  
Cao C(2021)undefined Nature 600 170-169
[6]  
Yang F(2021)undefined Nature 600 164-862
[7]  
Ranjan R(2017)undefined Trends Cell Biol. 27 851-602
[8]  
Green DP(2021)undefined Neurosci. Lett. 744 135544-139
[9]  
Shukla AK(2014)undefined Trends Biochem. Sci. 39 594-undefined
[10]  
Singh G(2011)undefined Trends Mol. Med. 17 126-undefined
12