Targeting Cell Senescence for the Treatment of Age-Related Bone Loss

被引:0
作者
Robert J. Pignolo
Rebekah M. Samsonraj
Susan F. Law
Haitao Wang
Abhishek Chandra
机构
[1] Mayo Clinic,Department of Medicine
[2] Mayo Clinic,Department of Physiology and Biomedical Engineering
[3] Mayo Clinic College of Medicine,Division of Geriatric Medicine & Gerontology
来源
Current Osteoporosis Reports | 2019年 / 17卷
关键词
Cell senescence; Osteoporosis; Aging; Telomere dysfunction; Senescence-associated secretory phenotype; Senolytic drug;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:70 / 85
页数:15
相关论文
共 946 条
[1]  
Boros K(2017)Physiology of ageing of the musculoskeletal system Best Pract Res Clin Rheumatol 31 203-217
[2]  
Freemont T(1991)Age-related bone changes Exp Gerontol 26 171-187
[3]  
Kiebzak GM(2012)Aging and bone loss: new insights for the clinician Ther Adv Musculoskelet Dis 4 61-76
[4]  
Demontiero O(2007)Age-related changes in trabecular architecture differ in female and male C57BL/6J mice J Bone Miner Res 22 1197-1207
[5]  
Vidal C(2013)Pathogenesis of age-related bone loss in humans J Gerontol A Biol Sci Med Sci 68 1226-1235
[6]  
Duque G(2016)Sclerostin and bone aging: a mini-review Gerontology 62 618-623
[7]  
Glatt V(2015)Vitamin D, muscle and bone: integrating effects in development, aging and injury Mol Cell Endocrinol 410 3-10
[8]  
Canalis E(2015)Skeletal stem cells Development (Cambridge, England) 142 1023-1027
[9]  
Stadmeyer L(2016)Ageing in the musculoskeletal system: cellular function and dysfunction throughout life Acta Orthop 87 15-25
[10]  
Bouxsein ML(2015)Determinants of muscle and bone aging J Cell Physiol 230 2618-2625