Abiraterone AcetateIn Metastatic Castration-Resistant Prostate Cancer

被引:0
|
作者
Lily P. H. Yang
机构
[1] Adis,
[2] a Wolters Kluwer Business,undefined
来源
Drugs | 2011年 / 71卷
关键词
Prednisone; Androgen Receptor; DHEA; Eplerenone; Abiraterone;
D O I
暂无
中图分类号
学科分类号
摘要
Oral abiraterone acetate, in combination with prednisone/prednisolone, is used to treat patients with metastatic castration-resistant prostate cancer (CRPC) who have previously received docetaxel-containing chemotherapy. Abiraterone acetate was developed to specifically inhibit cytochrome P450 (CYP)17A1, which is an essential enzyme in the biosynthesis of testosterone.
引用
收藏
页码:2067 / 2077
页数:10
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