Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis

被引：0
作者：
Takeshi Kezuka
Hitoshi Ishikawa
机构：
[1] KEZUKA Eye Clinic,Department of Ophthalmology
[2] Tokyo Medical University,Department of Orthoptics and Visual Science, School of Allied Health Sciences
[3] Kitasato University,undefined
来源：
Japanese Journal of Ophthalmology | 2018年 / 62卷
关键词：
Anti-myelin oligodendrocyte glycoprotein antibody; Anti-MOG antibody; Optic neuritis; Chronic recurrent inflammatory optic neuropathy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Anti-myelin-oligodendrocyte glycoprotein (MOG) antibody positive optic neuritis has been established as a new subset of optic neuropathy. Anti-MOG antibodies are usually measured by cell-based assay. Patients with anti-MOG antibody positive optic neuritis respond well to steroid therapy, and, while visual acuity outcomes are favorable, significant visual field defects remain. Furthermore, patients who are anti-MOG antibody positive have higher rates of recurrence compared to antibody negative patients. Based on these findings, anti-MOG antibody positive patients with optic neuritis have the characteristics of good visual outcomes, residual visual field defects, and high risk of recurrence. Tests for anti-MOG antibody are useful for the diagnosis and treatment of optic neuritis.
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页码：101 / 108
页数：7
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