Diabetes and brain aging: Epidemiologic evidence

被引：76
作者：
Launer L.J. [1 ]
机构：
[1] Lab. of Epidemiol. Demogr. Biometry, National Institute on Aging, Bethesda, MD 20892
来源：
Current Diabetes Reports | 2005年 / 5卷 / 1期
关键词：
Dementia; Brain Aging; Nondiabetic Patient; Cognitive Disorder; Midlife Blood Pressure;
D O I：
10.1007/s11892-005-0069-1
中图分类号：
学科分类号：
摘要：
Increasingly, data from epidemiologic studies suggest diabetes is a risk factor in old age for brain aging, including cognitive impairment and dementia. These associations may reflect a direct effect on the brain of hyperglycemia, or the effects of the diabetes-associated comorbidities of hypertension, dyslipidemia, or hyperinsulinemia. Epidemiologic data on diabetes and brain aging are reviewed. A brief overview is also given of the physiologic mechanisms supporting the epidemiologic data. Copyright © 2005 by Current Science Inc.
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页码：59 / 63
页数：4
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