Bilateral orbital myeloid sarcoma as initial manifestation of acute myeloid leukemia

被引：12

作者：

Hmidi K. ^{[1
]}

Zaouali S. ^{[2
]}

Messaoud R. ^{[1
]}

Mahjoub B. ^{[3
]}

Ammari W. ^{[1
]}

Bacha L. ^{[1
]}

Laatiri A. ^{[4
]}

Jenzeri S. ^{[1
]}

Khairallah M. ^{[2
]}

机构：

[1] Department of Ophthalmology, Tahar Sfar University Hospital

[2] Department of Ophthalmology, Fattouma Bourguiba University Hospital

[3] Department of Pediatry, Tahar Sfar University Hospital

[4] Department of Hematology, Farhat Hached University Hospital

来源：

International Ophthalmology | 2007年 / 27卷 / 6期

关键词：

Acute myeloblastic leukemia; Chemotherapy; Chloroma; Granulocytic sarcoma; Myelodysplastic syndrome; Orbital neoplasm;

D O I：

10.1007/s10792-007-9088-z

中图分类号：

学科分类号：

摘要：

Background: Granulocytic sarcoma is a rare orbital complication of acute leukemia. It concerns primarily children under 10 years of age suffering from primitive acute myeloid leukemia. The diagnosis is made by clinical examination, computed tomography and confirmed by haematological investigations. The treatment approach is based on chemotherapy associated with intravenous steroid therapy. Case report: We report the case of a 6-year-old girl who presented with bilateral proptosis revealing acute myeloid leukemia. The patient was treated by a combination of chemotherapeutic drugs in two phases, associated with intravenous steroids. After a follow-up period of 24 months, the patient was in complete remission. Conclusion: The diagnosis of granulocytic sarcoma should be considered in any orbital mass of uncertain origin, particularly if it is bilateral. Special stains and immunohistochemistry play an important role in the diagnosis. © Springer Science+Business Media B.V. 2007.

引用

页码：373 / 377

页数：4

共 37 条

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