How can we get more beta cells?

被引：9
作者：
Inada A. [1 ]
Bonner-Weir S. [1 ]
Toschi E. [1 ]
机构：
[1] Joslin Diabetes Center, Boston, MA 02215, One Joslin Place
来源：
Current Diabetes Reports | 2006年 / 6卷 / 2期
关键词：
Beta Cell; Hepatocyte Growth Factor; Acinar Cell; Human Islet; Protein Transduction Domain;
D O I：
10.1007/s11892-006-0018-7
中图分类号：
学科分类号：
摘要：
The need for a reliable source of functional β cells has led to many new investigations in an effort to drive the differentiation of embryonic stem cells, of putative stem cells, or of pancreatic progenitor cells to form new β cells. There appears to be a plasticity of pancreatic cells in vitro that may be exploited to generate the necessary β cells. Major questions still remain: whether there are true pancreatic stem cells, what are the pancreatic progenitor cells after birth, and whether expanded β cells themselves could serve as the source. Copyright © 2006 by Current Science Inc.
引用
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页码：96 / 101
页数：5
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