Synthesis and biological evaluation in vitro and in silico of N-propionyl-N′-benzeneacylhydrazone derivatives as cruzain inhibitors of Trypanosoma cruzi

Rassi A(2010)Chagas disease Lancet 375 1388-1402

Rassi A(2010)Chagas disease: 100 years after its discovery. A systemic review Acta Trop 115 5-13

Marin-Neto JA(2010)Chagas disease: a Latin American health problem becoming a world health problem Acta Trop 115 14-21

Coura JR(2010)Chagas disease in Spain, the United States and other non-endemic countries Acta Trop 115 22-27

Borges-Pereira J(2016)Quello che non si cerca difficilmente si trova: La malattia di Chagas G Ital Cardiol 17 343-347

Schmunis GA(2008)A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes Proc Natl Acad Sci 105 5022-5027

Yadon ZE(2010)Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches Acta Trop 115 55-68

Gascon J(2019)Facile synthesis of a series of non-symmetric thioethers including a benzothiazole moiety and their use as effcient in vitro anti-trypanosoma cruzi agents Molecules 24 3077-121

Bern C(2020)Synthesis, characterization and preliminary in vitro trypanocidal activity of N-arylfluorinated hydroxylated-Schiff bases J Mol Struct 1218 128520-11

Pinazo MJ(2009) targets for new chemotherapeutic approaches Expert Opin Ther Targets 13 105-898

Rassi A(2010)Chagas disease Lancet 375 1388-1402

Rassi A(2010)Chagas disease: 100 years after its discovery. A systemic review Acta Trop 115 5-13

Marin-Neto JA(2010)Chagas disease: a Latin American health problem becoming a world health problem Acta Trop 115 14-21

Coura JR(2010)Chagas disease in Spain, the United States and other non-endemic countries Acta Trop 115 22-27

Borges-Pereira J(2016)Quello che non si cerca difficilmente si trova: La malattia di Chagas G Ital Cardiol 17 343-347

Schmunis GA(2008)A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes Proc Natl Acad Sci 105 5022-5027

Yadon ZE(2010)Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches Acta Trop 115 55-68

Gascon J(2019)Facile synthesis of a series of non-symmetric thioethers including a benzothiazole moiety and their use as effcient in vitro anti-trypanosoma cruzi agents Molecules 24 3077-121

Bern C(2020)Synthesis, characterization and preliminary in vitro trypanocidal activity of N-arylfluorinated hydroxylated-Schiff bases J Mol Struct 1218 128520-11

Pinazo MJ(2009) targets for new chemotherapeutic approaches Expert Opin Ther Targets 13 105-898