Fenfluramine for the Treatment of Dravet Syndrome and Lennox Gastaut Syndrome: A Review

[1] Sultana B(2021)Incidence and prevalence of drug-resistant epilepsy: a systematic review and meta-analysis Neurology 96 805-817

[2] Cross JH(2021)Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome Seizure 93 154-159

[3] Fuller RW(1988)Mechanisms of effects of d-fenfluramine on brain serotonin metabolism in rats: uptake inhibition versus release Pharmacol Biochem Behav 30 715-721

[4] Snoddy HD(2015)Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine PLoS ONE 10 624-588

[5] Robertson DW(1966)Treatment of refractory obesity with fenfluramine BMJ 2 205-406

[6] Zhang Y(2002)Fenfluramine as a potential antiepileptic drug Epilepsia J Int League Against Epilepsy 43 581-1139

[7] Munro JF(1997)Valvular heart disease associated with fenfluramine–phentermine N Engl J Med 337 1419-231

[8] Seaton DA(1985)Treatment of self-induced photosensitive epilepsy with fenfluramine N Engl J Med 313 391-619

[9] Duncan LJ(1987)Compulsive respiratory stereotypies in children with autistic features: polygraphic recording and treatment with fenfluramine J Autism Dev Disord 17 1131-308

[10] Casaer P(2012)Successful use of fenfluramine as an add-on treatment for Dravet syndrome Epilepsia 53 228-14

[1] Sultana B(2021)Incidence and prevalence of drug-resistant epilepsy: a systematic review and meta-analysis Neurology 96 805-817

[2] Cross JH(2021)Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome Seizure 93 154-159

[3] Fuller RW(1988)Mechanisms of effects of d-fenfluramine on brain serotonin metabolism in rats: uptake inhibition versus release Pharmacol Biochem Behav 30 715-721

[4] Snoddy HD(2015)Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine PLoS ONE 10 624-588

[5] Robertson DW(1966)Treatment of refractory obesity with fenfluramine BMJ 2 205-406

[6] Zhang Y(2002)Fenfluramine as a potential antiepileptic drug Epilepsia J Int League Against Epilepsy 43 581-1139

[7] Munro JF(1997)Valvular heart disease associated with fenfluramine–phentermine N Engl J Med 337 1419-231

[8] Seaton DA(1985)Treatment of self-induced photosensitive epilepsy with fenfluramine N Engl J Med 313 391-619

[9] Duncan LJ(1987)Compulsive respiratory stereotypies in children with autistic features: polygraphic recording and treatment with fenfluramine J Autism Dev Disord 17 1131-308

[10] Casaer P(2012)Successful use of fenfluramine as an add-on treatment for Dravet syndrome Epilepsia 53 228-14