Dietary Approaches for Management of Non-Alcoholic Fatty Liver Disease: A Clinician’s Guide

被引:11
作者
Aboubakr A. [1 ,2 ]
Stroud A. [2 ]
Kumar S. [3 ]
Newberry C. [3 ]
机构
[1] Department of Internal Medicine, Weill Cornell Medical Center, 1320 York Avenue, Suite HT-621, New York, 10021, NY
[2] Division of Bariatric Surgery, Oregon Health & Science University, 3485 S. Bond Avenue, Portland, 97239, OR
[3] Division of Gastroenterology, Weill Cornell Medical Center, 1305 York Avenue, 4th Floor, New York, 10021, NY
关键词
Diet; Hepatic steatosis; Non-alcoholic fatty liver disease (NAFLD); Obesity; Weight loss;
D O I
10.1007/s11894-021-00827-0
中图分类号
学科分类号
摘要
Non-alcoholic fatty liver disease (NAFLD) is closely associated with obesity, insulin resistance, and hyperlipidemia. There is strong clinical evidence that reduction in at least 5–7% total body weight is associated with improvement in hepatic steatosis and regression of fibrosis, with weight loss representing the primary approach to treatment. This guide reviews recent data on dietary approaches studied in NAFLD management. The strongest evidence currently supports a hypocaloric diet to induce weight loss and subsequent improvement in liver enzymes and histology, as well as a Mediterranean diet, which can lead to improvement in steatosis even in the absence of weight reduction. The purpose of this paper is to provide clinicians with tools to engage patients in conversations about nutrition in the setting of NAFLD, ultimately guiding suitable personalized dietary recommendations. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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