Two Boys with 47, XXY and Autism

被引：0

作者：

S. L. Merhar

P. Manning-Courtney

机构：

[1] University of Pennsylvania Medical Center,Division of Developmental Disabilities

[2] Cincinnati Children’s Hospital Medical Center,House Staff Department

[3] Cincinnati Children’s Hospital Medical Center,undefined

来源：

Journal of Autism and Developmental Disorders | 2007年 / 37卷

关键词：

Autistic spectrum disorders; Autism; Epilepsy; EEG; Klinefelter syndrome;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Two children with autism and Klinefelter syndrome (KS) (47, XXY) are presented. Both qualify for the diagnosis of autism based on DSM-IV with severely delayed and disordered language, difficulties with social interaction, and a restricted range of interests and activities. Both also have abnormal EEGs, and one patient has had what appear to be clinical seizures. Trials of antiepileptic medications have not been beneficial in either patient. We report the clinical and EEG findings of each patient, and discuss the implications of this combination of disorders.

引用

页码：840 / 846

页数：6

共 50 条

[1] Two boys with 47, XXY and autism
Merhar, S. L.
Manning-Courtney, P.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2007, 37 (05) : 840 - 846
[2] Vulnerability for autism traits in boys and men with an extra X chromosome (47,XXY): The mediating role of cognitive flexibility
van Rijn, Sophie
Bierman, Marit
Bruining, Hilgo
Swaab, Hanna
JOURNAL OF PSYCHIATRIC RESEARCH, 2012, 46 (10) : 1300 - 1306
[3] Behavioral and Social Phenotypes in Boys With 47, XYY Syndrome or 47, XXY Klinefelter Syndrome
Ross, Judith L.
Roeltgen, David P.
Kushner, Harvey
Zinn, Andrew R.
Reiss, Allan
Bardsley, Martha Zeger
McCauley, Elizabeth
Tartaglia, Nicole
PEDIATRICS, 2012, 129 (04) : 769 - 778
[4] Novel Neurocognitive Profile in a Minority of Boys with 47,XXY (Klinefelter Syndrome)
Samango-Sprouse, Carole A.
Hamzik, Mary P.
Khaksari, Kosar
Brooks, Michaela R.
Sadeghin, Teresa
Gropman, Andrea L.
JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 2022, 43 (09) : E623 - E628
[5] Positive effects of early androgen therapy on the behavioral phenotype of boys with 47,XXY
Samango-Sprouse, Carole
Stapleton, Emily J.
Lawson, Patrick
Mitchell, Francie
Sadeghin, Teresa
Powell, Sherida
Gropman, Andrea L.
AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS, 2015, 169 (02) : 150 - 157
[6] Early androgen deficiency in infants and young boys with 47,XXY Klinefelter syndrome
Ross, JL
Samango-Sprouse, C
Lahlou, N
Kowal, K
Elder, FF
Zinn, A
HORMONE RESEARCH, 2005, 64 (01) : 39 - 45
[7] Expanding the phenotypic profile of boys with 47, XXY: The impact of familial learning disabilities
Samango-Sprouse, Carole A.
Stapleton, Emily J.
Mitchell, Francie L.
Sadeghin, Teresa
Donahue, Thomas P.
Gropman, Andrea L.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2014, 164 (06) : 1464 - 1469
[8] Testicular Dysfunction in 47,XXY Boys: When It All Begins. A Semilongitudinal Study
Pozza, Carlotta
Sesti, Franz
Tenuta, Marta
Spaziani, Matteo
Tarantino, Chiara
Carlomagno, Francesco
Minnetti, Marianna
Pofi, Riccardo
Paparella, Roberto
Lenzi, Andrea
Radicioni, Antonio
Isidori, Andrea M.
Tarani, Luigi
Gianfrilli, Daniele
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2023, 108 (10) : 2486 - 2499
[9] Autism traits and schizotypal traits in a genetic syndrome (47,XXY): the role of executive functioning
van Rijn, S.
Aleman, A.
de Sonneville, L.
Swaab, H.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2009, 53 : 837 - 837
[10] THE RELATIONSHIP BETWEEN 47, XXY (KLINEFELTER SYNDROME), AUTISM SPECTRUM TRAITS (AST), AND EARLY HORMONAL THERAPY (EHT)
Samango-Sprouse, C.
Tran, S.
Lasutschinkow, P.
Sadeghin, T.
Gropman, A.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2019, 63 (09) : 1084 - 1085

← 1 2 3 4 5 →