Lung-protective sedation: moving toward a new paradigm of precision sedation

[1] Wang W(2011)Estimating the causal effect of low tidal volume ventilation on survival in patients with acute lung injury J R Stat Soc: Ser C: Appl Stat 60 475-496

[2] Scharfstein D(2006)The relationship between sedative infusion requirements and permissive hypercapnia in critically ill, mechanically ventilated patients Crit Care Med 34 1668-1673

[3] Wang C(2016)Spontaneous breathing during mechanical ventilation- risks, mechanisms and management Am J Respir Crit Care Med 49 1137-1148

[4] Vinayak AG(2015)Asynchronies during mechanical ventilation are associated with mortality Intensive Care Med 49 2090-2101

[5] Gehlbach B(2018)Mechanical ventilation-induced diaphragm atrophy strongly impacts clinical outcomes Am J Respir Crit Care Med 143 927-938

[6] Pohlman AS(2021)Optimal sedation in patients who receive neuromuscular blocking agent infusions for treatment of acute respiratory distress syndrome-a retrospective cohort study from a new England health care network Crit Care Med 46 2338-2341

[7] Yoshida T(2021)Discordance between respiratory drive and sedation depth in critically ill patients receiving mechanical ventilation Crit Care Med 46 2314-2326

[8] Fujuno Y(2013)Mechanical ventilation-induced reverse-triggered breaths: a frequently unrecognized form of neuromechanical coupling Chest 203 67-77

[9] Amato M(2016)Effects of dexmedetomidine and propofol on patient-ventilator interaction in difficult-to-wean, mechanically ventilated patients: a prospective, open-label, randomized, multicentre study Crit Care 195 792-800

[10] Kavanagh B(2013)Impact of ventilator adjustment and sedation-analgesia practices on severe asynchrony in patients ventilated in assist-control mode Crit Care Med undefined undefined-undefined

[1] Wang W(2011)Estimating the causal effect of low tidal volume ventilation on survival in patients with acute lung injury J R Stat Soc: Ser C: Appl Stat 60 475-496

[2] Scharfstein D(2006)The relationship between sedative infusion requirements and permissive hypercapnia in critically ill, mechanically ventilated patients Crit Care Med 34 1668-1673

[3] Wang C(2016)Spontaneous breathing during mechanical ventilation- risks, mechanisms and management Am J Respir Crit Care Med 49 1137-1148

[4] Vinayak AG(2015)Asynchronies during mechanical ventilation are associated with mortality Intensive Care Med 49 2090-2101

[5] Gehlbach B(2018)Mechanical ventilation-induced diaphragm atrophy strongly impacts clinical outcomes Am J Respir Crit Care Med 143 927-938

[6] Pohlman AS(2021)Optimal sedation in patients who receive neuromuscular blocking agent infusions for treatment of acute respiratory distress syndrome-a retrospective cohort study from a new England health care network Crit Care Med 46 2338-2341

[7] Yoshida T(2021)Discordance between respiratory drive and sedation depth in critically ill patients receiving mechanical ventilation Crit Care Med 46 2314-2326

[8] Fujuno Y(2013)Mechanical ventilation-induced reverse-triggered breaths: a frequently unrecognized form of neuromechanical coupling Chest 203 67-77

[9] Amato M(2016)Effects of dexmedetomidine and propofol on patient-ventilator interaction in difficult-to-wean, mechanically ventilated patients: a prospective, open-label, randomized, multicentre study Crit Care 195 792-800

[10] Kavanagh B(2013)Impact of ventilator adjustment and sedation-analgesia practices on severe asynchrony in patients ventilated in assist-control mode Crit Care Med undefined undefined-undefined