Modified model of the structure of the potato virus X coat protein

被引：0
作者：
E. N. Dobrov
M. A. Nemykh
E. V. Lukashina
L. A. Baratova
V. A. Drachev
A. V. Efimov
机构：
[1] Moscow State University,Belozersky Institute of Physico
[2] Moscow State University,Chemical Biology
[3] Russian Academy of Sciences,Faculty of Bioengineering and Bioinformatics
来源：
Molecular Biology | 2007年 / 41卷
关键词：
potato virus X; model of coat protein structure;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A modified model was proposed for the tertiary structure of the coat protein (CP) molecules in potato virus X (PVX) virions, similar to the original model of 2001 describing the structure of CP of potato virus A, a member of another group of filamentous viruses. According to the new model, CP comprises two main structural domains, namely, a bundle of α-helices, located near the long axis of the virion, and the socalled RNP fold (or abCd fold), located in the vicinity of its surface. The model made it possible to suggest a possible mechanism of the PVX virion structural rearrangement (remodeling) resulting from translational activation of virions by the TGB1 movement protein according to Atabekov and colleagues.
引用
收藏
页码：638 / 641
页数：3
相关论文
共 126 条
  • [11] Arkhipenko M.V.(2004)N-terminal segment of potato virus X coat protein subunits is glycosylated and mediates formation of a bound water shell on the virion surface Eur. J. Biochem. 271 3136-3145
  • [12] Rodionova N.P.(2002)Solution structures of potato virus X and narcissus mosaic virus from Raman optical activity J. Gen. Virol. 83 241-246
  • [13] Karpova O.V.(2005)Structures of plant viruses from vibrational circular dichroism J. Gen. Virol. 86 2371-2377
  • [14] Kozlovsky S.V.(1987)A comparison between the predicted secondary structures of potato virus X and papaya mosaic virus coat protein J. Gen. Virol. 68 1229-1232
  • [15] Zayakina O.V.(1989)Structure of potyvirus coat proteins and its application in the taxonomy of the potyvirus group Adv. Virus Res. 36 273-314
  • [16] Arkhipenko M.V.(2006)Low cetyltrimethylammonium bromide concentrations induce reversible amorphous aggregation of tobacco mosaic virus and its coat protein at room temperature Int. J. Biochem. Cell. Biol. 38 533-543
  • [17] Atabekov J.G.(1989)Visualization of intact tobacco mosaic virus at 2.9 Å resolution by X-ray fiber diffraction J. Mol. Biol. 208 307-325
  • [18] Parker L.(1998)A comparative differential scanning calorimetric study of tobacco mosaic virus and of its coat protein ts mutant FEBS Lett. 433 307-311
  • [19] Kendall A.(1984)The current picture of the structure and assembly of tobacco mosaic virus J. Gen. Virol. 65 253-279
  • [20] Stubbs G.(1997)Proline-dependent oligomerization with arm exchange Structure. 5 391-401
12345678910