Modified model of the structure of the potato virus X coat protein

被引：0
作者：
E. N. Dobrov
M. A. Nemykh
E. V. Lukashina
L. A. Baratova
V. A. Drachev
A. V. Efimov
机构：
[1] Moscow State University,Belozersky Institute of Physico
[2] Moscow State University,Chemical Biology
[3] Russian Academy of Sciences,Faculty of Bioengineering and Bioinformatics
来源：
Molecular Biology | 2007年 / 41卷
关键词：
potato virus X; model of coat protein structure;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A modified model was proposed for the tertiary structure of the coat protein (CP) molecules in potato virus X (PVX) virions, similar to the original model of 2001 describing the structure of CP of potato virus A, a member of another group of filamentous viruses. According to the new model, CP comprises two main structural domains, namely, a bundle of α-helices, located near the long axis of the virion, and the socalled RNP fold (or abCd fold), located in the vicinity of its surface. The model made it possible to suggest a possible mechanism of the PVX virion structural rearrangement (remodeling) resulting from translational activation of virions by the TGB1 movement protein according to Atabekov and colleagues.
引用
收藏
页码：638 / 641
页数：3
相关论文
共 126 条
  • [1] Atabekov J.G.(2000)The movement protein-triggered in situ conversion of potato virus X virion RNA from a nontranslatable into a translatable form Virology. 271 259-263
  • [2] Rodionova N.P.(2001)Translational activation of encapsidated potato virus X RNA by coat protein phosphorylation Virology. 286 466-474
  • [3] Karpova O.V.(2003)Linear remodeling of helical virus by movement protein binding J. Mol. Biol 333 565-572
  • [4] Kozlovsky S.V.(2002)Surface features of potato virus X from fiber diffraction Virology. 300 291-295
  • [5] Poljakov V.Yu.(2007)Comparative structural stability of subunits of the potato virus X coat protein in solution and in virus particles Mol. Biol. 41 630-637
  • [6] Atabekov J.G.(1992)The organization of potato virus X coat proteins in virus particles studied by tritium planigraphy and model building Virology. 188 175-180
  • [7] Rodionova N.P.(2001)In situ spatial organization of potato virus A coat protein subunits as assessed by tritium bombardment J. Virol. 75 9696-9702
  • [8] Karpova O.V.(1993)Standard structures in proteins Prog. Biophys. Mol. Biol. 60 201-239
  • [9] Kozlovsky S.V.(1995)Structural similarity between twolayer α/β and β-proteins J. Mol. Biol. 245 402-415
  • [10] Novikov V.K.(1999)Complementary packing of α-helices in proteins FEBS Lett. 463 3-6
12345678910