The domestic dog: man's best friend in the genomic era

被引：0
作者：
Adam R Boyko
机构：
[1] Stanford University,Department of Genetics
来源：
Genome Biology | / 12卷
关键词：
Genetic Architecture; Causal Variant; Gray Wolf; Degenerative Myelopathy; Qualitative Trait Locus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The domestic dog genome - shaped by domestication, adaptation to human-dominated environments and artificial selection - encodes tremendous phenotypic diversity. Recent developments have improved our understanding of the genetics underlying this diversity, unleashing the dog as an important model organism for complex-trait analysis.
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[21]  
Alvarez P(2010)Canine morphology: hunting for genes and tracking mutations PLoS Biol 8 e1000310-231
[22]  
Biagi T(2006)Relaxation of selective constraint on dog mitochondrialDNA following domestication Genome Res 16 990-460
[23]  
Brockman W(2008)The legacy of domestication: accumulation of deleterious mutations in the dog genome Mol Biol Evol 25 2331-1808
[24]  
Butler J(2009)Complex population structure in African village dogs and its implications for inferring dog domestication history Proc Natl Acad Sci USA 106 13903-336
[25]  
Chin CW(2006)A fetching model organism Cell 124 229-998
[26]  
Cook A(2007)Elevated basal slippage mutation rates among the Canidae J Hered 98 452-153
[27]  
Cuff J(2005)Short interspersed elements (SINEs) are a major source of canine genomic diversity Genome Res 15 1798-115
[28]  
Daly MJ(2010)Man's best friend becomes biology's best in show: genome analyses in the domestic dog Annu Rev Genet 44 309-1423
[29]  
DeCaprio D(2010)Localization of canine brachycelphaly using an across breed mapping approach PLoS One 5 e9632-1320
[30]  
Gnerre S(2009)An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs Science 325 995-1165
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