Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E

被引:0
作者
Jerome Robert
Emily B. Button
Emma M. Martin
Luke McAlary
Zoe Gidden
Megan Gilmour
Guilaine Boyce
Tara M. Caffrey
Andrew Agbay
Amanda Clark
Judith M. Silverman
Neil R. Cashman
Cheryl L. Wellington
机构
[1] University of British Columbia,Department of Pathology and Laboratory Medicine
[2] University of British Columbia,Djavad Mowafaghian Centre for Brain Health
[3] University Hospital Zurich,Present address: Institute of Clinical Chemistry
[4] University of British Columbia,Department of Physics and Astronomy
[5] University of British Columbia,Department of Neurology
[6] University of British Columbia,School of Biomedical Engineering
[7] University of British Columbia,International Collaboration on Repair Discoveries
来源
Molecular Neurodegeneration | / 15卷
关键词
Alzheimer’s disease; Cerebrovasculature; High-density lipoprotein (HDL); Cerebral amyloid angiopathy (CAA); Endothelial inflammation; Apolipoprotein (apo)E; Tissue engineering;
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[1]  
Sevigny J(2016)The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease Nat Publ Group 537 50-56
[2]  
Di Francesco JC(2015)Anti-Aβ autoantibodies in amyloid related imaging abnormalities (ARIA): candidate biomarker for immunotherapy in Alzheimer’s disease and cerebral amyloid angiopathy Front Neurol 6 4-6
[3]  
Longoni M(2007)Ankle-to-brachial index and dementia: the Honolulu-Asia aging study Circulation 116 2269-2274
[4]  
Piazza F(2011)Cerebral amyloid angiopathy: a systematic review J Clin Neurol 7 1-9
[5]  
Laurin D(2019)Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction Nat Med 25 270-276
[6]  
Masaki KH(2007)Transport pathways for clearance of human Alzheimer’s amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system J Cereb Blood Flow Metab 27 909-918
[7]  
White LR(2019)Vascular dysfunction—the disregarded partner of Alzheimer’s disease Alzheimer’s Dementia 15 158-167
[8]  
Launer LJ(2017)Pathophysiologic relationship between Alzheimer’s disease, cerebrovascular disease, and cardiovascular risk: a review and synthesis Alzheimers Dement 7 69-87
[9]  
Biffi A(2019)Favorable cardiovascular health at young and middle ages and dementia in older age—the CHA study J Am Heart Assoc 8 e009730-583
[10]  
Greenberg SM(2018)Antihypertensive medication regimen intensity and incident dementia in an older population J Am Med Dir Assoc 19 577-469