Fight or flight turns hair white

被引:5
作者
Clark, Shayla A. [1 ]
Deppmann, Christopher D. [1 ,2 ,3 ,4 ]
机构
[1] Univ Virginia, Neurosci Grad Program, Charlottesville, VA 22903 USA
[2] Univ Virginia, Dept Biol, Charlottesville, VA USA
[3] Univ Virginia, Dept Biomed Engn, Charlottesville, VA USA
[4] Univ Virginia, Dept Cell Biol & Neurosci, Charlottesville, VA USA
关键词
SYMPATHETIC-NERVOUS-SYSTEM;
D O I
10.1038/d41586-019-03949-8
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Signalling from the sympathetic nervous system of mice when subjected to stress leads to the depletion of a stem-cell population in their hair follicles. This discovery sheds light on why stress turns hair prematurely grey.
引用
收藏
页码:623 / 624
页数:2
相关论文
共 16 条
  • [11] Dominant role of the niche in melanocyte stem-cell fate determination
    Nishimura, EK
    Jordan, SA
    Oshima, H
    Yoshida, H
    Osawa, M
    Moriyama, M
    Jackson, IJ
    Barrandon, Y
    Miyachi, Y
    Nishikawa, S
    [J]. NATURE, 2002, 416 (6883) : 854 - 860
  • [12] A neuroendocrinological perspective on human hair follicle pigmentation
    Paus, Ralf
    [J]. PIGMENT CELL & MELANOMA RESEARCH, 2011, 24 (01) : 89 - 106
  • [13] Melanin
    Riley, PA
    [J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 1997, 29 (11) : 1235 - 1239
  • [14] A DEMOGRAPHIC-ANALYSIS OF MALE LIFE-HISTORY AND SOCIAL-STRUCTURE OF MOUNTAIN GORILLAS
    ROBBINS, MM
    [J]. BEHAVIOUR, 1995, 132 : 21 - 47
  • [15] SHAW N A, 1974, Laboratory Animals (London), V8, P1, DOI 10.1258/002367774780943913
  • [16] Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells
    Zhang, Bing
    Ma, Sai
    Rachmin, Inbal
    He, Megan
    Baral, Pankaj
    Choi, Sekyu
    Goncalves, William A.
    Shwartz, Yulia
    Fast, Eva M.
    Su, Yiqun
    Zon, Leonard I.
    Regev, Aviv
    Buenrostro, Jason D.
    Cunha, Thiago M.
    Chiu, Isaac M.
    Fisher, David E.
    Hsu, Ya-Chieh
    [J]. NATURE, 2020, 577 (7792) : 676 - +