Fight or flight turns hair white

被引：5
作者：
Clark, Shayla A. [1 ]
Deppmann, Christopher D. [1 ,2 ,3 ,4 ]
机构：
[1] Univ Virginia, Neurosci Grad Program, Charlottesville, VA 22903 USA
[2] Univ Virginia, Dept Biol, Charlottesville, VA USA
[3] Univ Virginia, Dept Biomed Engn, Charlottesville, VA USA
[4] Univ Virginia, Dept Cell Biol & Neurosci, Charlottesville, VA USA
来源：
NATURE | 2020年 / 577卷 / 7792期
关键词：
SYMPATHETIC-NERVOUS-SYSTEM;
D O I：
10.1038/d41586-019-03949-8
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Signalling from the sympathetic nervous system of mice when subjected to stress leads to the depletion of a stem-cell population in their hair follicles. This discovery sheds light on why stress turns hair prematurely grey.
引用
收藏
页码：623 / 624
页数：2
相关论文
共 16 条
  • [1] Risk Factors for Premature Hair Graying in Young Turkish Adults
    Belli, Asli Akin
    Etgu, Fatma
    Gok, Seyran Ozbas
    Kara, Bilge
    GursoyDogan
    [J]. PEDIATRIC DERMATOLOGY, 2016, 33 (04) : 438 - 442
  • [2] Cunningham P, 1997, CHEM ENG-LONDON, P5
  • [3] Daulatabad Deepashree, 2017, Int J Trichology, V9, P19, DOI 10.4103/ijt.ijt_79_16
  • [4] Science and society - Stress-induced immune dysfunction: implications for health
    Glaser, R
    Kiecolt-Glaser, JK
    [J]. NATURE REVIEWS IMMUNOLOGY, 2005, 5 (03) : 243 - 251
  • [5] Chronic variable stress activates hematopoietic stem cells
    Heidt, Timo
    Sager, Hendrik B.
    Courties, Gabriel
    Dutta, Partha
    Iwamoto, Yoshiko
    Zaltsman, Alex
    von zur Muhlen, Constantin
    Bode, Christoph
    Fricchione, Gregory L.
    Denninger, John
    Lin, Charles P.
    Vinegoni, Claudio
    Libby, Peter
    Swirski, Filip K.
    Weissleder, Ralph
    Nahrendorf, Matthias
    [J]. NATURE MEDICINE, 2014, 20 (07) : 754 - 758
  • [6] Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow
    Katayama, Y
    Battista, M
    Kao, WM
    Hidalgo, A
    Peired, AJ
    Thomas, SA
    Frenette, PS
    [J]. CELL, 2006, 124 (02) : 407 - 421
  • [7] Anxiety and impulsivity: Factors associated with premature graying in young dogs
    King, Camille
    Smith, Thomas J.
    Grandin, Temple
    Borchelt, Peter
    [J]. APPLIED ANIMAL BEHAVIOUR SCIENCE, 2016, 185 : 78 - 85
  • [8] Mendez-Ferrer S, 2008, BLOOD, V112, P4
  • [9] Nahm Michael, 2013, Int J Trichology, V5, P63, DOI 10.4103/0974-7753.122959
  • [10] Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche
    Nishimura, EK
    Granter, SR
    Fisher, DE
    [J]. SCIENCE, 2005, 307 (5710) : 720 - 724
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