CRNDE: an oncogenic long non-coding RNA in cancers

被引：0
|
作者：
Ya Lu
Huanhuan Sha
Xun Sun
Yuan Zhang
Yang Wu
Junying Zhang
Hui Zhang
Jianzhong Wu
Jifeng Feng
机构：
[1] Nanjing Medical University Affiliated Cancer Hospital & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research,
[2] The Forth Clinical School of Nanjing Medical University,undefined
来源：
Cancer Cell International | / 20卷
关键词：
CRNDE; lncRNA; Cancer; Biomarker;
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学科分类号：
摘要：
Colorectal neoplasia differentially expressed (CRNDE) is a long non-coding RNA which has been proved upregulated in various cancers. Meanwhile, CRNDE has been demonstrated to be involved in multiple biological processes of different cancers according to previous study. Moreover, recent studies suggested CRNDE might be a potential diagnostic biomarker and prognostic predictor due to its high sensitivity and specificity in cancer tissues and plasma. In this review, we summarize the biological function of CRNDE and the relevant mechanisms in cancers to establish a molecular basis for the clinical use of CRNDE in the future.
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