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- [42] The Effectiveness of a Weak Opioid Medication versus a Cyclo-oxygenase-2 (COX-2) Selective Non-steroidal Anti-inflammatory Drug in Treating Flare-up of Chronic Low-back Pain: Results from Two Randomized, Double-blind, 6-week Studies JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2009, 37 (06) : 1789 - 1802