Safety and efficacy of a single intra-articular injection of a novel enhanced protein solution (JTA-004) compared to hylan G-F 20 in symptomatic knee osteoarthritis: a randomized, double-blind, controlled phase II/III study

被引：0

作者：

Marie Bettonville

Marc Léon

Joëlle Margaux

Didier Urbin-Choffray

Emilie Theunissen

Tatiana Besse-Hammer

Yves Fortems

Séverine Verlinden

Olivier Godeaux

Anne-Sophie Delmarcelle

Jean-François Kaux

机构：

[1] Bone Therapeutics S.A,Physical and Rehabilitation Medicine & Sport Traumatology Department

[2] Current Address: iTeos Belgium SA,undefined

[3] CHU Ambroise Paré,undefined

[4] CUB Erasme,undefined

[5] CHR Citadelle,undefined

[6] Clinique Saint-Pierre Ottignies,undefined

[7] CHU Brugmann,undefined

[8] AZ Sint-Jozef,undefined

[9] CHR Haute Senne,undefined

[10] Current Address: ZAM Consulting,undefined

[11] Current Address: Cryotherapeutics SA,undefined

[12] University and University Hospital of Liège,undefined

来源：

BMC Musculoskeletal Disorders | / 22卷

关键词：

Knee osteoarthritis; Clinical trial; Intra-articular injection; Hyaluronic acid; Clonidine; Human plasma;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 28 条

[21] A Multicenter, Randomized, Double-Blinded, Parallel-Group, Placebo-Controlled Phase I/IIa Study to Evaluate the Efficacy and Safety of a Single Intra-Articular Injection of YYD302 in Patients with Knee Osteoarthritis
In, Yong
Ha, Chul-Won
JOURNAL OF CLINICAL MEDICINE, 2022, 11 (06)
[22] Treatment of knee osteoarthritis with intra-articular injection of autologous adipose-derived mesenchymal progenitor cells: a prospective, randomized, double-blind, active-controlled, phase IIb clinical trial
Liangjing Lu
Chengxiang Dai
Zhongwen Zhang
Hui Du
Suke Li
Ping Ye
Qiong Fu
Li Zhang
Xiaojing Wu
Yuru Dong
Yang Song
Dongbao Zhao
Yafei Pang
Chunde Bao
Stem Cell Research & Therapy, 10
[23] Efficacy of intra-articular injection of allogeneic platelet-rich plasma for knee osteoarthritis combined with hematologic blood dyscrasias with platelet dysfunction: protocol of a randomized, double-blind, placebo-controlled trial
Zhu, Xiaohang
Zhao, Lingying
Liu, An
Yu, Ziqiang
Guo, Jiong Jiong
BMC MUSCULOSKELETAL DISORDERS, 2022, 23 (01)
[24] Efficacy of intra-articular injection of allogeneic platelet-rich plasma for knee osteoarthritis combined with hematologic blood dyscrasias with platelet dysfunction: protocol of a randomized, double-blind, placebo-controlled trial
Xiaohang Zhu
Lingying Zhao
An Liu
Ziqiang Yu
Jiong Jiong Guo
BMC Musculoskeletal Disorders, 23
[25] Three once-weekly intra-articular injections of Hylan G-F 20 significantly improve pain relief compared with placebo in patients with chronic idiopathic knee osteoarthritis: a single-centre, evaluator-blinded and patient-blinded, randomized controlled trial
Langworthy, Michael
Lascarides, Peter
Ngai, Wilson
Steele, Kevin
Huang, Yili
DRUGS IN CONTEXT, 2024, 13
[26] Comparing the Efficacy of Intra-Articular Single Platelet-Rich Plasma(PRP) versus Novel Crosslinked Hyaluronic Acid for Early-Stage Knee Osteoarthritis: A Prospective, Double-Blind, Randomized Controlled Trial
Wang, Ying-Chun
Lee, Chia-Ling
Chen, Yu-Jen
Tien, Yin-Chun
Lin, Sung-Yen
Chen, Chung-Hwan
Chou, Paul Pei-Hsi
Huang, Hsuan-Ti
MEDICINA-LITHUANIA, 2022, 58 (08):
[27] Intra-articular injection of the anti-inflammatory compound LMWF-5A in adults with severe osteoarthritis: A double-blind prospective randomized controlled multi-center safety and efficacy trial
Salottolo K.
Cole B.
Bar-Or D.
Patient Safety in Surgery, 12 (1)
[28] Efficacy of a Novel Intra-Articular Administration of Platelet-Rich Plasma One-Week Prior to Hyaluronic Acid versus Platelet-Rich Plasma Alone in Knee Osteoarthritis: A Prospective, Randomized, Double-Blind, Controlled Trial
Wu, Yung-Tsan
Li, Tsung-Ying
Lee, Kuei-Chen
Lam, King Hei Stanley
Chang, Chih-Ya
Chang, Cheng-Kuang
Chen, Liang-Cheng
JOURNAL OF CLINICAL MEDICINE, 2022, 11 (11)

← 1 2 3 →