Structural and functional genome organization and life cycle of hepatitis C virus

被引:0
作者
O. V. Kalinina
A. V. Dmitriev
机构
[1] St. Petersburg Pasteur Institute,
[2] Almazov Northwest Federal Medical Research Center,undefined
[3] Federal State Budgetary Scientific Institution Institute of Experimental Medicine,undefined
[4] St. Petersburg State Technological Institute (Technical University),undefined
来源
Molecular Genetics, Microbiology and Virology | 2015年 / 30卷
关键词
hepatitis C virus; functional genome organization; polyprotein; life cycle;
D O I
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中图分类号
学科分类号
摘要
Modern data on hepatitis C virus genome and polyprotein organization are summarized in this review. The functional roles of structural and nonstructural virus proteins, including their interaction with cellular regulatory proteins and structural cell elements, are described. Special features of the life cycle of the hepatitis C virus (that supplement our knowledge of viral hepatitis C pathogenesis) are presented.
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页码:64 / 70
页数:6
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