Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

被引：0
|
作者：
Xueming Li
Paul Mooney
Shawn Zheng
Christopher R Booth
Michael B Braunfeld
Sander Gubbens
David A Agard
Yifan Cheng
机构：
[1] The Keck Advanced Microscopy Laboratory,Department of Biochemistry and Biophysics
[2] University of California,undefined
[3] San Francisco (UCSF),undefined
[4] Gatan Inc.,undefined
[5] The Howard Hughes Medical Institute (HHMI),undefined
[6] UCSF,undefined
来源：
Nature Methods | 2013年 / 10卷
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摘要：
The combination of a direct electron-detection camera that can count individual electrons and an algorithm for correcting for beam-induced motion in cryo-EM will facilitate determination of three-dimensional structures of smaller, lower-symmetry macromolecular complexes to higher resolution than previously possible.
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页码：584 / 590
页数：6
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