Probing when dCas9 tolerates DNA mismatches

被引:0
|
作者
Weihua Guan
机构
[1] Pennsylvania State University,Departments of Electrical Engineering and Biomedical Engineering
来源
Nature Biomedical Engineering | 2024年 / 8卷
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学科分类号
摘要
Sensing changes in ionic current as barcoded DNA translocates through solid-state nanopores allows the study of how nucleotide sequences alter the DNA-binding specificity of the catalytically inactive Cas9 ribonucleoprotein complex.
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页码:207 / 208
页数:1
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