Differences in histological features and PD-L1 expression between sporadic microsatellite instability and Lynch-syndrome-associated disease in Japanese patients with colorectal cancer

[1] Le DT(2015)PD-1 blockade in tumors with mismatch-repair deficiency N Engl J Med 372 2509-2520

[2] Uram JN(1993)Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome Cancer Res 53 5853-5855

[3] Wang H(1996)Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients Nat Med 2 169-174

[4] Peltomäki P(1998)Incidence and functional consequences of MLH1 promoter hypermethylation in colorectal carcinoma Proc Natl Acad Sci USA 95 6870-6875

[5] Lothe RA(2013)Lynch syndrome-associated colorectal carcinoma: frequent involvement of the left colon and rectum and late-onset presentation supports a universal screening approach Hum Pathol 44 2518-2528

[6] Aaltonen LA(2002)Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status Nature 418 934-428

[7] Liu B(2008)The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations Gastroenterology 135 419-109

[8] Parsons R(2004)Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer Cancer Lett 211 105-2116

[9] Papadopoulos N(2001)Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis Am J Pathol 159 2107-866

[10] Herman JG(2002)Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability Eur J Cancer 38 858-1417

[1] Le DT(2015)PD-1 blockade in tumors with mismatch-repair deficiency N Engl J Med 372 2509-2520

[2] Uram JN(1993)Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome Cancer Res 53 5853-5855

[3] Wang H(1996)Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients Nat Med 2 169-174

[4] Peltomäki P(1998)Incidence and functional consequences of MLH1 promoter hypermethylation in colorectal carcinoma Proc Natl Acad Sci USA 95 6870-6875

[5] Lothe RA(2013)Lynch syndrome-associated colorectal carcinoma: frequent involvement of the left colon and rectum and late-onset presentation supports a universal screening approach Hum Pathol 44 2518-2528

[6] Aaltonen LA(2002)Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status Nature 418 934-428

[7] Liu B(2008)The clinical phenotype of Lynch syndrome due to germ-line PMS2 mutations Gastroenterology 135 419-109

[8] Parsons R(2004)Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer Cancer Lett 211 105-2116

[9] Papadopoulos N(2001)Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis Am J Pathol 159 2107-866

[10] Herman JG(2002)Distinction between familial and sporadic forms of colorectal cancer showing DNA microsatellite instability Eur J Cancer 38 858-1417