Combination of Aqueous and Non-Aqueous Capillary Electrophoresis with Electrospray Mass Spectrometry for the Determination of Drug Residues in Water

被引：0

作者：

Werner Ahrer

Wolfgang Buchberger

机构：

[1] University of Linz,

[2] Department of Analytical Chemistry,undefined

[3] A-4040 Linz,undefined

[4] Austria,undefined

来源：

Monatshefte für Chemie / Chemical Monthly | 2001年 / 132卷

关键词：

Keywords. Drug residues; Water analysis; Non-aqueous capillary electrophoresis; Electrospray ionization mass spectrometry.;

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摘要：

The work presented in this paper deals with the combination of capillary electrophoresis (CE) with electrospray mass spectrometry (MS) for the determination of drug residues in water. CE/MS methods have been developed based on either aqueous or non-aqueous ammonium acetate solutions as the carrier electrolyte for the separation of selected drugs. The different separation conditions were compared in terms of selectivity and detection limits; both aqueous and non-aqueous CE proved to be suitable for the present analytical task, exhibiting detection limits between 3 and 93 μg/dm3 (injected standard concentration) corresponding to concentrations between 5 and 19 ng/dm3 in the sample.

引用

页码：329 / 337

页数：8