Diagnosis and treatment of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a frequent complication of liver cirrhosis. Worldwide HCC is one of the most common cancers with a rising incidence. Rapid recognition of HCC and the earliest possible treatment are decisive for the further course. Both treatment of the tumor and the underlying chronic liver disease, including preservation of liver function, are important for the management of patients with HCC. Standard stage-adapted treatments include liver resection, transplantation, and interventional treatment such as thermal ablation and transarterial therapy. In the advanced stage, treatment with the tyrosinekinase inhibitor sorafenib is the standard of care.