Diagnosis of MalariaChallenges for Clinicians in Endemic and Non-Endemic Regions

被引:0
作者
Rachel N. Bronzan
Meredith L. McMorrow
S. Patrick Kachur
机构
[1] National Center for Zoonotic Vector-Borne and Enteric Diseases,United States Public Health Service, Malaria Branch, Division of Parasitic Diseases
[2] Centers for Disease Control and Prevention,undefined
来源
Molecular Diagnosis & Therapy | 2008年 / 12卷
关键词
Malaria; Entomologic Inoculation Rate; Malaria Diagnosis; Antimalarial Agent; Plasmodium Knowlesi;
D O I
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中图分类号
学科分类号
摘要
Malaria is a leading cause of morbidity and mortality worldwide. Prompt diagnosis and treatment are critical factors in reducing morbidity and mortality, as delayed treatment of malaria increases the risk of death. Microscopy has long been the standard of malaria diagnosis, but newer diagnostic tests now offer advantages in certain settings. Malaria diagnosis is complicated by the fact that acquired immunity to malaria can result in asymptomatic infections. In a symptomatic (febrile) patient, no existing malaria diagnostic test can distinguish malarial illness from parasitemia with concomitant fever of another cause. In this review we discuss the available malaria diagnostic tests, appropriate applications for each, and the challenges of malaria diagnosis in both endemic and non-endemic settings.
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页码:299 / 306
页数:7
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