Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells

被引:0
作者
Jing Li
Tian-xiang Li
Yao Ma
Yong Zhang
De-yuan Li
Hai-rong Xu
机构
[1] Yangzhou University,Institute of Translational Medicine, Medical College
[2] Yangzhou University,Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases
[3] Kangda College of Nanjing Medical University,Department of Clinical Medicine
[4] Nanjing Agricultural University,Key Lab of Animal Disease Diagnosis and Immunology, Ministry of Agriculture, College of Veterinary Medicine
[5] Yangzhou University,Jiangsu Co
来源
Cancer Cell International | / 19卷
关键词
Apoptosis; Endoplasmic reticulum stress; G1 cell cycle arrest; Mitochondrial pathway; Reactive oxygen species;
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  • [1] Jemal A(2010)Cancer statistics, 2010 CA Cancer J Clin 60 277-300
  • [2] Siegel R(2009)Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer N Engl J Med 360 1408-1417
  • [3] Xu J(2018)Targeting nicotinamide Mol Ther Nucleic Acids. 11 455-467
  • [4] Ward E(2018)-methyltransferase and miR-449a in EGFR-TKI-resistant non-small-cell lung cancer cells Mol Ther Nucleic Acids. 12 817-828
  • [5] Van Cutsem E(2005)BMP4 upregulation is associated with acquired drug resistance and fatty acid metabolism in EGFR-mutant non-small-cell lung cancer cells Eur J Cancer 41 1969-1979
  • [6] Kohne CH(2013)Mechanisms and preclinical efficacy of silibinin in preventing skin cancer Cancer Lett. 332 295-303
  • [7] Hitre E(2017)Targeting apoptosis pathways by natural compounds in cancer. Marine compounds as lead structures and chemical tools for cancer therapy Cancer Lett 400 325-335
  • [8] Zaluski J(2001)Naturally occurring anti-cancer agents targeting EZH2 Phytochemistry 56 237-243
  • [9] Chang Chien CR(2011)Phytochemistry and medicinal plants Amino Acids 40 505-515
  • [10] Makhson A(2011)Immunomodulatory activities of a new pentapeptide (Bursopentin) from the chicken bursa of Fabricius Clin Vaccine Immunol 18 1497-1502