TGFβ Signaling Pathways and Human Diseases

被引：0

作者：

Richard W. Padgett

机构：

[1] Rutgers University,Waksman Institute, The Department of Molecular Biology and Biochemistry, and The Cancer Institute of New Jersey

来源：

Cancer and Metastasis Reviews | 1999年 / 18卷

关键词：

TGFβ; Smads; cancer; development; growth factors;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Recent progress in deciphering the TGFβ pathway has uncovered a new signaling molecule, the Smads, and with this finding now gives us insights into how TGFβ-like signals are transmitted from outside the cell to the nucleus. As we learn more about how TGFβ regulates normal development, we also are gaining insights into diseases that are caused by mis-regulation or mutation of various components of the signaling pathways.

引用

页码：247 / 259

页数：12

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