Modification of treatment strategy after FFR measurement: CVIT-DEFER registry

被引：12

作者：

Nakamura M. ^{[1
]}

Yamagishi M. ^{[2
]}

Ueno T. ^{[3
]}

Hara K. ^{[4
]}

Ishiwata S. ^{[5
]}

Itoh T. ^{[6
]}

Hamanaka I. ^{[7
]}

Wakatsuki T. ^{[8
]}

Sugano T. ^{[9
]}

Kawai K. ^{[10
]}

Akasaka T. ^{[11
]}

Tanaka N. ^{[12
]}

Kimura T. ^{[13
]}

机构：

[1] Division of Cardiovascular Medicine, Ohashi Medical Center, Toho University School of Medicine, 2-17-6 Ohashi, Meguro-ku, Tokyo

[2] Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Kanazawa

[3] Center of Cardiovascular Medicine, Kurume University Hospital, Kurume

[4] Division of Internal Medicine, Mitsui Memorial Hospital, Tokyo

[5] Division of Cardiology, Cardiovascular Center, Toranomon Hospital, Tokyo

[6] Division of Cardiology, Department of Internal Medicine and Memorial Heart Center, Iwate Medical University, Morioka

[7] Rakuwakai Marutamachi Hospital, Rakuwakai Kyoto Cardiovascular Intervention Center, Kyoto

[8] Department of Cardiovascular Medicine, Institute of Health Biosciences, University of Tokushima, Tokushima

[9] Department of Cardiology, Yokohama City University Hospital, Yokohama

[10] Department of Cardiovascular Medicine, Chikamori Hospital, Kochi

[11] Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama

[12] Department of Cardiology, Tokyo Medical University, Tokyo

[13] Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto

来源：

Cardiovascular Intervention and Therapeutics | 2015年 / 30卷 / 1期

关键词：

Angiography; Coronary artery stenosis; Fractional flow reserve; Functional coronary artery stenosis; Treatment strategy;

D O I：

10.1007/s12928-014-0266-4

中图分类号：

学科分类号：

摘要：

The impact of the fractional flow reserve (FFR) on clinical decision-making remains unclear in daily practice. The CVIT-DEFER registry is a prospective multicenter registry enrolling consecutive patients with angiographically intermediate coronary stenosis for whom FFR measurement is clinically indicated. The treatment strategy determined from angiographic findings alone and the strategy selected after FFR measurement were compared. Data on the treatment strategy were obtained for 3093 subjects. The average age of these subjects was 69.5 ± 10.2 years and 73.8 % were men. The majority had stable coronary artery disease, including 60.4 % with stable angina pectoris. The treatment strategy based on angiographic findings was medical management in 34.5 %, percutaneous coronary intervention (PCI) in 63.5 %, and coronary artery bypass grafting in 2.1 %. The FFR was ≤0.8 in 1566 lesions (42.2 %). After FFR measurement, medical treatment was changed to revascularization in 19.7 %, while PCI was switched to medical treatment in 57.4 % at the lesion level. As a result, reclassification of the treatment strategy at the patient level was done in 39.0 % of the patients. Revascularization was frequently switched to medical treatment after FFR measurement. These findings support the clinical utility of employing FFR data to guide selection of PCI. © 2014, Japanese Association of Cardiovascular Intervention and Therapeutics.

引用

页码：12 / 21

页数：9

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