Management of Hypertension in the Elderly

被引:0
作者
Aronow W.S. [1 ]
机构
[1] Cardiology Division, New York Medical College, Macy Pavilion, Room 138, Valhalla, 10595, NY
关键词
Antihypertensive treatment; Blood pressure; Elderly; Heart failure; Hypertension; Myocardial infarction; Stroke;
D O I
10.1007/s12170-015-0469-y
中图分类号
学科分类号
摘要
Recommendations for the management of hypertension in the elderly are largely consistent with the exception of the 2013 Joint National Committee (JNC) 8 guidelines that recommend lowering systolic blood pressure (SBP) in persons aged ≥60 years to <150 mmHg if they do not have diabetes mellitus or chronic kidney disease. In contrast, I concur with the minority view from JNC 8 which recommends a SBP goal in these persons aged 60 to 79 years of <140 mmHg. This view is consistent with the 2011 American College of Cardiology/American Heart Association (ACC/AHA) guidelines that also recommend a SBP goal of 140 to 145 mmHg if tolerated in adults aged ≥80 years. ACC/AHA consensus guidelines use the totality of evidence in addition to randomized controlled trial data. These guidelines are also consistent with treatment recommendations from numerous other societies that recommend SBP goals of <140 mmHg in persons aged 60 to 79 years and <150 mmHg in persons aged ≥80 years. Hypertension is currently under-treated in the elderly, and relaxation of ACC/AHA guidelines by JNC 8 will result in substantially more cardiovascular events. Randomized clinical trial studies on treatment of essential hypertension or secondary hypertension in frail elderly persons have not been performed. © 2015, Springer Science+Business Media New York.
引用
收藏
页数:8
相关论文
共 51 条
[1]  
Aronow W.S., Fleg J.L., Pepine C.J., Artinian N.T., Bakris G., Brown A.S., Et al., ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus documents developed in collaboration with the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologi
[2]  
Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP), JAMA, 265, pp. 3255-3264, (1991)
[3]  
Perry H.M., Davis B.R., Price T.R., Applegate W.B., Fields W.S., Guralnik J.M., Et al., Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke. The Systolic Hypertension in the Elderly Program (SHEP), JAMA, 284, pp. 465-471, (2000)
[4]  
Kostis J.B., Davis B.R., Cutler J., Grimm R.H., Berge K.G., Cohen J.D., Et al., Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension, JAMA, 278, pp. 212-216, (1997)
[5]  
Beckett N.S., Peters R., Fletcher A.E., Staessen J.A., Liu L., Dumitrascu D., Et al., Treatment of hypertension in patients 80 years of age or older, N Eng J Med, 358, pp. 1887-1898, (2008)
[6]  
Law M.R., Morris J.K., Wald N.J., Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies, BMJ, 338, (2009)
[7]  
Mancia G., Fagard R., Narkiewicz K., Redon J., Zanchetti A., Bohm M., Et al., 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC), Eur Heart J, 34, pp. 2159-2219, (2013)
[8]  
James P.A., Oparil S., Carter B.L., Cushman W.C., Dennison-Himmelfarb C., Handler J., Et al., 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8), JAMA, 311, pp. 507-520, (2014)
[9]  
Wright J.T., Fine L.J., Lackland D.T., Ogedegbe G., Dennison-Himmelfarb C., Evidence supporting a systolic blood pressure goal of less than 150 mmHg in patients aged 60 years or older: the minority view, Ann Intern Med, 160, pp. 499-503, (2014)
[10]  
Hackam D.G., Quinn R.R., Ravani P., Rabi D.M., Dasgupta K., Daskalopoulou S.S., Et al., The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension, Can J Cardiol, 29, pp. 528-542, (2013)