Atrial remodeling and atrial fibrillation recurrence after catheter ablation: Past, present, and future developments; [Atriales Remodeling und Rezidiv des Vorhofflimmerns nach Katheterablation: Entwicklungen der Vergangenheit, Gegenwart und Zukunft]

被引：0
作者：
Nedios S. [1 ]
Lindemann F. [1 ]
Heijman J. [2 ]
Crijns H.J.G.M. [2 ]
Bollmann A. [1 ]
Hindricks G. [1 ]
机构：
[1] Department of Electrophysiology, Heart Center at University of Leipzig, Strümpellstr. 39, Leipzig
[2] Department of Cardiology, CardiovascularResearch Institute Maastricht (CARIM), Maastricht University Medical Center, Maastricht
来源：
Herz | 2021年 / 46卷 / 4期
关键词：
Diastolic dysfunction; Left atrium; Patient care; Personalized medicine; Precision medicine;
D O I：
10.1007/s00059-021-05050-1
中图分类号：
学科分类号：
摘要：
The term “atrial remodeling” is used to describe the electrical, mechanical, and structural changes associated with the presence of an arrhythmogenic substrate for atrial fibrillation. Rhythm control therapy may slow down or even reverse progressive atrial remodeling. Atrial remodeling has long been recognized as an important predictor of clinical outcomes and therapeutic success, but recent advances have highlighted its clinical relevance and revealed the implications of specific anatomical changes such as atrial asymmetry or shape. This has opened the path to computational precision medicine that captures these data in detail and combines them with other factors, to provide patient-specific solutions. The goal of precision medicine lies in improving clinical outcomes, reducing costs, and avoiding unnecessary procedures. In this article, we review the history of atrial remodeling and we summarize the insights from our research on anatomical atrial remodeling and its association with rhythm outcomes after catheter ablation. Finally, we present recent advances in the field, reflecting the beginning of a new technological era that will enable us to improve patient care by personalized patient-specific medicine. © 2021, Springer Medizin Verlag GmbH, ein Teil von Springer Nature.
引用
收藏
页码：312 / 317
页数：5
相关论文
共 50 条
  • [1] Kirchhof P., Benussi S., Kotecha D., Et al., 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO), Eur Heart J, (2016)
  • [2] Ball J., Carrington M.J., McMurray J.J., Stewart S., Atrial fibrillation: profile and burden of an evolving epidemic in the 21st century, Int J Cardiol, 167, 5, pp. 1807-1824, (2013)
  • [3] Schnabel R.B., Yin X., Gona P., Et al., 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study, Lancet, 386, 9989, pp. 154-162, (2015)
  • [4] Benjamin E.J., Wolf P.A., D'Agostino R.B., Et al., Impact of atrial fibrillation on the risk of death: the Framingham Heart Study, Circulation, 98, 10, pp. 946-952, (1998)
  • [5] Andersson T., Magnuson A., Bryngelsson I.L., Et al., All-cause mortality in 272,186 patients hospitalized with incident atrial fibrillation 1995–2008: a Swedish nationwide long-term case-control study, Eur Heart J, 34, 14, pp. 1061-1067, (2013)
  • [6] Marzona I., O'Donnell M., Teo K., Et al., Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies, CMAJ, 184, 6, pp. E329-E336, (2012)
  • [7] von Eisenhart Rothe A., Hutt F., Baumert J., Et al., Depressed mood amplifies heart-related symptoms in persistent and paroxysmal atrial fibrillation patients: a longitudinal analysis—data from the German Competence Network on Atrial Fibrillation, Europace, 17, 9, pp. 1354-1362, (2015)
  • [8] Bollmann A., First comes diagnosis then comes treatment: an underappreciated paradigm in atrial fibrillation management, Eur Heart J, 26, 23, pp. 2487-2489, (2005)
  • [9] Henry W.L., Morganroth J., Pearlman A.S., Et al., Relation between echocardiographically determined left atrial size and atrial fibrillation, Circulation, 53, 2, pp. 273-279, (1976)
  • [10] Morillo C.A., Klein G.J., Jones D.L., Guiraudon C.M., Chronic rapid atrial pacing. Structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation, Circulation, 91, 5, pp. 1588-1595, (1995)
12345