Single genome retrieval of context-dependent variability in mutation rates for human germline

被引:0
作者
Aleksandr B. Sahakyan
Shankar Balasubramanian
机构
[1] University of Cambridge,Department of Chemistry
[2] University of Cambridge,Cancer Research UK Cambridge Institute
[3] University of Cambridge,School of Clinical Medicine
来源
BMC Genomics | / 18卷
关键词
Nucleotide substitutions; Spontaneous mutations; Germline; Context-dependence; Genome composition; Somatic mutations; Cancer;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 303 条
[51]  
Zollner S(2013)Deciphering signatures of mutational processes operative in human cancer Cell Rep 3 246-5
[52]  
Enard W(2013)EMu: probabilistic inference of mutational processes and their localization in the cancer genome Genome Biol 14 39-9
[53]  
Ebersberger I(2014)Patterns and processes of somatic mutations in nine major cancers BMC Med Genom 7 11-33
[54]  
Nickel B(2011)COSMIC: mining complete cancer genomes in the catalogue of somatic mutations in cancer Nucl Acids Res 39 945-6
[55]  
Paabo S(1990)The mutational spectrum of single base-pair substitutions causing human genetic disease: patterns and predictions Human Genet 85 55-40
[56]  
Fryxell KJ(2009)Mutation patterns in cancer genomes Proc Natl Acad Sci USA 106 21766-1414
[57]  
Moon WJ(2002)Mutation rates in mammalian genomes Proc Natl Acad Sci USA 99 803-55
[58]  
Mugal CF(2013)Genome dynamics during experimental evolution Nat Rev Genet 14 827-1073
[59]  
Ellegren H(2013)Properties and rates of germline mutations in humans Trends Genet 29 575-36
[60]  
Lercher MJ(2015)The origins, determinants, and consequences of human mutations Science 349 1478-undefined