Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase

被引：0
作者：
Stephanie M Stanford
Alexander E Aleshin
Vida Zhang
Robert J Ardecky
Michael P Hedrick
Jiwen Zou
Santhi R Ganji
Matthew R Bliss
Fusayo Yamamoto
Andrey A Bobkov
Janna Kiselar
Yingge Liu
Gregory W Cadwell
Shilpi Khare
Jinghua Yu
Antonio Barquilla
Thomas D Y Chung
Tomas Mustelin
Simon Schenk
Laurie A Bankston
Robert C Liddington
Anthony B Pinkerton
Nunzio Bottini
机构：
[1] La Jolla Institute for Allergy and Immunology,Division of Cellular Biology
[2] University of California,Department of Medicine
[3] Infectious and Inflammatory Disease Center,Department of Respiratory
[4] Sanford Burnham Prebys Medical Discovery Institute,Department of Orthopaedic Surgery and Department of Pediatrics
[5] Conrad Prebys Center for Chemical Genomics,undefined
[6] Sanford Burnham Prebys Medical Discovery Institute,undefined
[7] Center for Proteomics and Bioinformatics,undefined
[8] Case Western Reserve University,undefined
[9] Institute for Genetic Medicine,undefined
[10] University of Southern California,undefined
[11] Inflammation and Autoimmunity,undefined
[12] MedImmune LLC,undefined
[13] University of California,undefined
来源：
Nature Chemical Biology | 2017年 / 13卷
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学科分类号：
摘要：
The generation of low-molecular-weight protein tyrosine phosphatase (LMPTP) knockout mice combined with the identification of a small-molecule uncompetitive LMPTP inhibitor reveals a role for LMPTP in regulating insulin resistance.[graphic not available: see fulltext]
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页码：624 / 632
页数：8
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