Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

被引:0
|
作者
Kazuko Haga
Andrew C. Kruse
Hidetsugu Asada
Takami Yurugi-Kobayashi
Mitsunori Shiroishi
Cheng Zhang
William I. Weis
Tetsuji Okada
Brian K. Kobilka
Tatsuya Haga
Takuya Kobayashi
机构
[1] Faculty of Science,Department of Life Science
[2] Gakushuin University,Department of Molecular and Cellular Physiology
[3] Mejiro 1-5-1,Department of Medical Chemistry and Cell Biology
[4] Tokyo 171-8588,Department of Structural Biology
[5] Japan,undefined
[6] Stanford University School of Medicine,undefined
[7] 279 Campus Drive,undefined
[8] Kyoto University Faculty of Medicine,undefined
[9] Konoe-cho,undefined
[10] Yoshdida,undefined
[11] Sakyo-Ku,undefined
[12] Kyoto 606-8501,undefined
[13] Japan,undefined
[14] Human Receptor Crystallography Project,undefined
[15] ERATO,undefined
[16] Japan Science and Technology Agency,undefined
[17] Konoe-cho,undefined
[18] Yoshida,undefined
[19] Sakyo-Ku,undefined
[20] Kyoto 606-8501,undefined
[21] Japan,undefined
[22] Graduate School of Pharmaceutical Sciences,undefined
[23] Kyushu University,undefined
[24] 3-1-1 Maidashi,undefined
[25] Higashi-ku,undefined
[26] Fukuoka 812-8582,undefined
[27] Japan,undefined
[28] Stanford University School of Medicine,undefined
[29] 299 Campus Drive,undefined
[30] Japan Science and Technology Agency,undefined
[31] Core Research for Evolutional Science and Technology (CREST),undefined
[32] Kyoto University Faculty of Medicine,undefined
[33] Kyoto 606-8501,undefined
[34] Japan,undefined
来源
Nature | 2012年 / 482卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The X-ray crystal structure of the M2 muscarinic acetylcholine receptor, which is essential for the physiological control of cardiovascular function, is reported.
引用
收藏
页码:547 / 551
页数:4
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