Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

被引：0

作者：

Kazuko Haga

Andrew C. Kruse

Hidetsugu Asada

Takami Yurugi-Kobayashi

Mitsunori Shiroishi

Cheng Zhang

William I. Weis

Tetsuji Okada

Brian K. Kobilka

Tatsuya Haga

Takuya Kobayashi

机构：

[1] Faculty of Science,Department of Life Science

[2] Gakushuin University,Department of Molecular and Cellular Physiology

[3] Mejiro 1-5-1,Department of Medical Chemistry and Cell Biology

[4] Tokyo 171-8588,Department of Structural Biology

[5] Japan,undefined

[6] Stanford University School of Medicine,undefined

[7] 279 Campus Drive,undefined

[8] Kyoto University Faculty of Medicine,undefined

[9] Konoe-cho,undefined

[10] Yoshdida,undefined

[11] Sakyo-Ku,undefined

[12] Kyoto 606-8501,undefined

[13] Japan,undefined

[14] Human Receptor Crystallography Project,undefined

[15] ERATO,undefined

[16] Japan Science and Technology Agency,undefined

[17] Konoe-cho,undefined

[18] Yoshida,undefined

[19] Sakyo-Ku,undefined

[20] Kyoto 606-8501,undefined

[21] Japan,undefined

[22] Graduate School of Pharmaceutical Sciences,undefined

[23] Kyushu University,undefined

[24] 3-1-1 Maidashi,undefined

[25] Higashi-ku,undefined

[26] Fukuoka 812-8582,undefined

[27] Japan,undefined

[28] Stanford University School of Medicine,undefined

[29] 299 Campus Drive,undefined

[30] Japan Science and Technology Agency,undefined

[31] Core Research for Evolutional Science and Technology (CREST),undefined

[32] Kyoto University Faculty of Medicine,undefined

[33] Kyoto 606-8501,undefined

[34] Japan,undefined

来源：

Nature | 2012年 / 482卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The X-ray crystal structure of the M2 muscarinic acetylcholine receptor, which is essential for the physiological control of cardiovascular function, is reported.

引用

页码：547 / 551

页数：4

共 50 条

[1] Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
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