Early HIV Infections Among Men Who Have Sex with Men in Five Cities in the United States

被引：0

作者：

G. Paz-Bailey

A. Smith

S. Masciotra

W. Zhang

T. Bingham

C. Flynn

D. German

A. Al-Tayyib

M. Magnus

M. LaLota

C. E. Rose

S. M. Owen

机构：

[1] Centers for Disease Control and Prevention,Department of Health, Behavior and Society

[2] Dynamic Research Corporation,Denver Public Health

[3] Department of Public Health,School of Public Health and Health Services

[4] Maryland Department of Health & Mental Hygiene,undefined

[5] Johns Hopkins Bloomberg School of Public Health,undefined

[6] Denver Health and Hospital Authority,undefined

[7] George Washington University,undefined

[8] Florida Department of Health,undefined

来源：

AIDS and Behavior | 2015年 / 19卷

关键词：

HIV; Acute; Early; Recent; MSM; NHBS; United States; African American;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

We tested blood samples from men who have sex with men (MSM) to detect early HIV infection. Early HIV included both acute (infected past 30 days) and recent (estimated recency past 240 days). Acute infections were defined as screen immunoassay (IA) negative/NAAT-positive or IA-positive/Multispot-negative/NAAT-positive. Recent infections were defined as avidity index cutoff <30 % on an avidity-based IA and, (1) not reporting antiretroviral therapy use or, (2) HIV RNA >150 copies/mL. Of 937 samples, 26 % (244) were HIV-infected and of these 5 % (12) were early. Of early infections, 2 were acute and 10 recent; most (8/12) were among black MSM. Early infection was associated with last partner of black race [adjusted relative risk (ARR) = 4.6, confidence intervals (CI) 1.2–17.3], receptive anal sex at last sex (ARR = 4.3, CI 1.2–15.0), and daily Internet use to meet partners/friends (ARR = 3.3, CI 1.1–9.7). Expanding prevention and treatment for black MSM will be necessary for reducing incidence in the United States.

引用

页码：2304 / 2310

页数：6

共 65 条

[1]

Powers KA(2011)The role of acute and early HIV infection in the spread of HIV and implications for transmission prevention strategies in Lilongwe, Malawi: a modelling study Lancet 378 256-268

[2]

Ghani AC(2013)HIV-1 transmission during early infection in men who have sex with men: a phylodynamic analysis PLoS Med 10 e1001568-822

[3]

Miller WC(2012)Factors associated with incorrect identification of recent HIV infection using the BED capture immunoassay AIDS Res Hum Retroviruses 28 816-239

[4]

Volz EM(2013)HIV incidence determination in the United States: a multiassay approach J Infect Dis 207 232-107

[5]

Ionides E(2012)Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates Open AIDS J. 6 98-1019

[6]

Romero-Severson EO(2006)Greater risk for HIV infection of black men who have sex with men: a critical literature review Am J Public Health 96 1007-637

[7]

Brandt MG(2013)Performance of a limiting-antigen avidity enzyme immunoassay for cross-sectional estimation of HIV incidence in the United States PLoS One 8 e82772-348

[8]

Mokotoff E(2009)Racial mixing and HIV risk among men who have sex with men AIDS Behav 13 630-52

[9]

Koopman JS(2012)Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: a meta-analysis Lancet 380 341-114

[10]

Laeyendecker O(2003)The effect of partner characteristics on HIV infection among African American men who have sex with men in the Young Men’s Survey, Los Angeles, 1999–2000 AIDS Educ Prev 15 39-2678

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