microRNA regulation of mammalian target of rapamycin expression and activity controls estrogen receptor function and RAD001 sensitivity

[1] Dunlop EA(2009)Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms Cellular signalling 21 827-835

[2] Tee AR(2010)mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs Science 328 1172-1176

[3] Dowling RJ(2011)mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways Cancer research 71 3246-3256

[4] Topisirovic I(2004)Upstream and downstream of mTOR Genes & development 18 1926-1945

[5] Alain T(2011)AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 Nature cell biology 13 132-141

[6] Bidinosti M(2010)Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress Molecular cell 40 310-322

[7] Fonseca BD(2009)A complex interplay between Akt, TSC2 and the two mTOR complexes Biochemical Society transactions 37 217-222

[8] Petroulakis E(2008)The TSC1-TSC2 complex is required for proper activation of mTOR complex 2 Molecular and cellular biology 28 4104-4115

[9] Wang X(2009)Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors Cancer research 69 6107-6114

[10] Larsson O(2010)mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling Molecular and cellular biology 30 908-921

[1] Dunlop EA(2009)Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms Cellular signalling 21 827-835

[2] Tee AR(2010)mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs Science 328 1172-1176

[3] Dowling RJ(2011)mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways Cancer research 71 3246-3256

[4] Topisirovic I(2004)Upstream and downstream of mTOR Genes & development 18 1926-1945

[5] Alain T(2011)AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 Nature cell biology 13 132-141

[6] Bidinosti M(2010)Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress Molecular cell 40 310-322

[7] Fonseca BD(2009)A complex interplay between Akt, TSC2 and the two mTOR complexes Biochemical Society transactions 37 217-222

[8] Petroulakis E(2008)The TSC1-TSC2 complex is required for proper activation of mTOR complex 2 Molecular and cellular biology 28 4104-4115

[9] Wang X(2009)Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors Cancer research 69 6107-6114

[10] Larsson O(2010)mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling Molecular and cellular biology 30 908-921