Synthesis of β-cycloalkylglycosides of Muramyl Dipeptide

被引：0
|
作者：
A. E. Zemlyakov
V. N. Tsikalova
V. V. Tsikalov
机构：
[1] V. I. Vernadsky Crimean Federal University,
来源：
Chemistry of Natural Compounds | 2017年 / 53卷
关键词：
glycosides of ; -acetylglucosamine; oxazoline synthesis; muramyl dipeptide; glycosides of muramyl dipeptide;
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学科分类号：
摘要：
β-Cyclooctyl-, β-cyclodecyl-, and β-cyclopentadecylglycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine were prepared in yields of 39, 18, and 25%, respectively, (calculated for muramic acid) via the reaction of β-cycloalkyl-4,6-O-isopropylidene-N-acetyl-D-muramic acids with the benzyl ester of L-Ala-D-iGln using the HOSu/DCC method followed by deprotection.
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页码：929 / 932
页数：3
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