Human anti-CAIX antibodies mediate immune cell inhibition of renal cell carcinoma in vitro and in a humanized mouse model in vivo

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作者
De-Kuan Chang
Raymond J. Moniz
Zhongyao Xu
Jiusong Sun
Sabina Signoretti
Quan Zhu
Wayne A. Marasco
机构
[1] Dana-Farber Cancer Institute,Department of Cancer Immunology and AIDS
[2] Harvard Medical School,Department of Medicine
[3] Dana-Farber Cancer Institute,Department of Medical Oncology
[4] Harvard Medical School,Department of Pathology, Brigham and Women’s Hospital
来源
Molecular Cancer | / 14卷
关键词
Orthotopic tumor; NSG mouse; Antibody engineering; Carbonic anhydrase IX; Immunotherapy; Xenograft;
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