Herbal seizures" - Atypical symptoms after ibogaine intoxication: A case report"

被引：10

作者：

Breuer L. ^{[3
,4
]}

Kasper B.S. ^{[3
,5
]}

Schwarze B. ^{[6
]}

Gschossmann J.M. ^{[7
]}

Kornhuber J. ^{[3
]}

Müller H.H. ^{[1
,2
]}

机构：

[1] Medical Campus University of Oldenburg, School of Medicine and Health Sciences Psychiatry and Psychotherapy, University Hospital Karl-Jaspers-Klinik, Hermann-Ehlers-Strasse 7, Bad Zwischenahn

[2] Friedrich-Alexander University of Erlangen-Nuremberg, Erlangen

[3] Department of Neurology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen

[4] Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen

[5] Epilepsy Center, Department of Neurology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen

[6] Department of Forensic Medicine, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen

[7] Department of Internal Medicine, Klinikum Forchheim, Friedrich-Alexander Universität Erlangen-Nuremberg, Erlangen

来源：

Journal of Medical Case Reports | / 9卷 / 1期

关键词：

Ibogaine misuse; Intoxication; Reactive seizures; Side effects;

D O I：

10.1186/s13256-015-0731-4

中图分类号：

学科分类号：

摘要：

Introduction: Misuse of various new psychotropic substances such as ibogaine is increasing rapidly. Knowledge of their negative side effects is sparse. Case presentation: We present a case of intoxication with the herbal substance ibogaine in a 22-year-old white man. After taking a cumulative dose of 38 g (taken in two doses), he developed visual memories, nausea and vomiting. He developed a generalized tonic-clonic seizure with additional grand mal seizures. He was treated with midazolam and levetiracetam. Extended drug screenings and computed tomography and magnetic resonance imaging findings were all negative. Conclusions: Knowledge of the side effects of ibogaine has mainly come from reports of cardiovascular complications; seizures are rarely mentioned and experimental findings are inconsistent. It seems that ibogaine acts like a proconvulsive drug at high doses. © 2015 Breuer et al.

引用

共 26 条

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