Targeting the transcriptional activity of STAT3 by a novel fusion protein

被引：0
作者：
Yanqiong Chen
Wenting Zhang
Xiufeng Bai
Yi Liu
机构：
[1] Sichuan University,National Clinical Research Center for Geriatrics and Laboratory of Human Disease and Immunotherapies, West China Hospital
[2] West China Hospital,Research Institute of Inflammation and Immunology (RIII), Frontiers Science Center for Disease
[3] Sichuan University,related Molecular Network
[4] Sichuan University,Rare Diseases Center, West China Hospital
来源：
BMC Cancer | / 22卷
关键词：
KRAB; STAT3; Transcription; cancer; Autoimmune diseases; Neurodegenerative diseases; Male infertility;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 228 条
[1]  
Bai L(2019)A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo Cancer Cell 36 498-511.e417
[2]  
Zhou H(2021)Combinations take Centre stage in PD1/PDL1 inhibitor clinical trials Nat Rev Drug Discov 20 168-169
[3]  
Xu R(2019)The current state and future directions of RNAi-based therapeutics Nat Rev Drug Discov 18 421-446
[4]  
Zhao Y(2013)Multiplex genome engineering using CRISPR/Cas systems Science 339 819-823
[5]  
Chinnaswamy K(2020)Targeting STAT3 in Cancer immunotherapy Mol Cancer 19 145-8155
[6]  
McEachern D(2011)Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1 PLoS One 6 e20188-3798
[7]  
Chen J(2005)STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3 Proc Natl Acad Sci U S A 102 8150-925
[8]  
Yang CY(2008)Identification of novel direct Stat3 target genes for control of growth and differentiation J Biol Chem 283 3791-23
[9]  
Liu Z(2014)STAT3 target genes relevant to human cancers Cancers (Basel) 6 897-2058
[10]  
Wang M(2018)The STAT3 inhibitor pyrimethamine displays anti-cancer and immune stimulatory effects in murine models of breast cancer Cancer Immunol Immunother 67 13-1124
12345678910