Epigenetic control of stem cell fate to neurons and glia

被引：0
|
作者：
Hyun-Jung Kim
Michael G. Rosenfeld
机构：
[1] Chung-Ang University,Laboratory of Molecular and Stem Cell Pharmacology, College of Pharmacy
[2] School of Medicine,Howard Hughes Medical Institute
[3] University of California,Department of Cellular and Molecular Medicine
[4] San Diego,undefined
[5] School of Medicine,undefined
来源：
Archives of Pharmacal Research | 2010年 / 33卷
关键词：
Histone modification; Non-coding RNA; Stem cell; Neuron; Glia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
How a cell fate is determined and how tremendously diverse cells are generated during development are interesting and intriguing questions to be solved before using the stem cells for therapeutic purpose. Recently, it has been suggested that epigenetic control by the histone modifying enzymes and non-coding RNAs play important roles in guiding stem cells to differentiate into neurons or glia. In this review, we discuss the recent outcomes and advances in understanding the histone modifying enzymes and non-coding RNAs during neural cell-type specification of stem cells.
引用
收藏
页码：1467 / 1473
页数：6
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